Resource Type

Journal Article 76

Year

2023 12

2022 5

2021 5

2020 5

2019 9

2018 6

2017 4

2016 1

2015 4

2014 1

2013 5

2012 1

2010 2

2008 5

2007 4

2006 3

2000 1

open ︾

Keywords

metabolic 4

Disturbance observer 3

diabetes 3

FGF21 2

Neural network 2

disturbance 2

disturbance compensation 2

insulin resistance 2

metabolic pathways 2

metabolic reprogramming 2

metabolism 2

metabolites 2

metabolomics 2

obesity 2

1 1

2 1

4-trichlorobenzen 1

Bifidobacterium 1

AA 1

open ︾

Search scope:

排序: Display mode:

Polycystic ovary syndrome

Zi-Jiang CHEN, Yuhua SHI

Frontiers of Medicine 2010, Volume 4, Issue 3,   Pages 280-284 doi: 10.1007/s11684-010-0098-2

Abstract: PCOS has additional metabolic derangements, such as insulin resistance, impaired glucose tolerance, andThe risks of diabetes, cardiovascular disease, hypertension, metabolic syndrome, and endometrial cancer

Keywords: polycystic ovary syndrome     genetics     metabolic disturbance    

Modal disturbance investigation of rod-shaped ultrasonic motor using bending vibrations

ZHANG Jiantao, ZHU Hua, ZHAO Chunsheng

Frontiers of Mechanical Engineering 2008, Volume 3, Issue 3,   Pages 343-347 doi: 10.1007/s11465-008-0058-6

Abstract: Modal disturbance of a rod-shaped ultrasonic motor using bending vibrations can cause problems such asAccordingly, the structure parameters of the stator are modified to separate working modes from disturbanceThe frequency separation between working modes and disturbance modes is more than 2 kHz.

Keywords: Hamilton principle     disturbance     separation     frequency separation     dynamic analysis    

New insights into different surfactants’ impacts on sludge fermentation: Focusing on the particular metabolic

Frontiers of Environmental Science & Engineering 2022, Volume 16, Issue 8, doi: 10.1007/s11783-022-1527-6

Abstract:

• The promoting effects for VFA generation follow the order of APG>SDBS>HTAB.

Keywords: Waste activated sludge (WAS)     Volatile fatty acids (VFA)     Surfactant types     Functional microorganisms     Metabolic    

Metabolic hypertension: concept and practice

Zhiming Zhu, Peijian Wang, Shuangtao Ma

Frontiers of Medicine 2013, Volume 7, Issue 2,   Pages 201-206 doi: 10.1007/s11684-013-0264-4

Abstract: More than 60% of the risk factors for hypertension are associated with metabolic disturbances.Metabolic abnormalities increase the risk for hypertension and cause high blood pressure.Improving metabolic disturbances is beneficial for hypertension treatment.Due to the importance of metabolic abnormalities in the pathogenesis of hypertension, we propose a conceptof metabolic hypertension.

Keywords: hypertension     cardiometabolic risk factors     metabolic abnormalities    

Beneficial metabolic activities of inflammatory cytokine interleukin 15 in obesity and type 2 diabetes

Jianping Ye

Frontiers of Medicine 2015, Volume 9, Issue 2,   Pages 139-145 doi: 10.1007/s11684-015-0377-z

Abstract:

In obesity, chronic inflammation is believed to induce insulin resistance and impairs adipose tissue function. Although this view is supported by a large body of literature, it has been challenged by growing evidence that pro-inflammatory cytokines may favor insulin sensitivity through induction of energy expenditure. In this review article, interleukin 15 (IL-15) is used as a new example to explain the beneficial effects of the pro-inflammatory cytokines. IL-15 is secreted by multiple types of cells including macrophages, neutrophils and skeletal muscle cells. IL-15 expression is induced in immune cells by endotoxin and in muscle cells by physical exercise. Its transcription is induced by transcription factor NF-κB. IL-15 binds to its receptor that contains three different subunits (α, β and γ) to activate JAK/STAT, PI3K/Akt, IKK/NF-κB and JNK/AP1 pathways in cells. In the regulation of metabolism, IL-15 reduces weight gain without inhibiting food intake in rodents. IL-15 suppresses lipogenesis, stimulates brown fat function, improves insulin sensitivity through weight loss and energy expenditure. In human, circulating IL-15 is negatively associated with body weight. In the immune system, IL-15 stimulates proliferation and differentiation of T cells, NK cells, monocytes and neutrophils. In the anti-obesity effects of IL-15, T cells and NK cells are not required, but leptin receptor is required. In summary, evidence from human and rodents supports that the pro-inflammatory cytokine IL-15 may enhance energy expenditure to protect the body from obesity and type 2 diabetes. The mechanism of IL-15 action remains to be fully uncovered in the regulation of energy expenditure.

Keywords: inflammation     obesity     cytokine     energy expenditure     insulin resistance    

electron transfer and its application in dictating routes of biochemical processes associated with metabolic

Frontiers of Medicine 2021, Volume 15, Issue 5,   Pages 679-692 doi: 10.1007/s11684-021-0866-1

Abstract: Metabolic reprogramming, such as abnormal utilization of glucose, addiction to glutamine, and increasedelectron transfer (PET), which is used to characterize the degree of electron redistribution coupled with metabolicEnabling electron transfer could drive metabolic reprogramming in cancer metabolism.

Keywords: metabolic reprogramming     potential of electron transfer     cell proliferation     aerobic glycolysis     cancer    

Virtual reality system of manned maneuvering unit taking into consideration the disturbance from an astronaut

CHENG Jian, FAN Xiu-min, XU An, HONG Xin, HUANG Wei-dong

Frontiers of Mechanical Engineering 2006, Volume 1, Issue 3,   Pages 282-287 doi: 10.1007/s11465-006-0042-y

Abstract: Based on the dynamics/kinematics model of an astronaut equipped with an MMU, a disturbance model of theFinally, the paper presents two different results between loading and unloading the disturbance model

Keywords: real-time emendation     disturbance     maneuvering     MMU     correction    

Fibroblast growth factor 21: a novel metabolic regulator from pharmacology to physiology

Huating Li, Jing Zhang, Weiping Jia

Frontiers of Medicine 2013, Volume 7, Issue 1,   Pages 25-30 doi: 10.1007/s11684-013-0244-8

Abstract: relevance of FGF21 in humans is still unclear, and the basis and consequences of increased FGF21 in metabolicpharmacological actions and physiological roles make FGF21 attractive drug candidates for treating metabolic

Keywords: FGF21     metabolism     pharmacology     physiology     clinical relevance    

Application of a Novel Fuzzy Clustering Method Based on Chaos Immune Evolutionary Algorithm for Edge Detection in Image Processing

Frontiers of Mechanical Engineering 2006, Volume 1, Issue 1,   Pages 85-89 doi: 10.1007/s11465-005-0023-6

Abstract: In CIEFCM, a tiny disturbance is added to a filial generation group using a chaos variable and the disturbance

Keywords: disturbance amplitude     disturbance     diversity     generation     processing    

Metformin and metabolic diseases: a focus on hepatic aspects

Juan Zheng,Shih-Lung Woo,Xiang Hu,Rachel Botchlett,Lulu Chen,Yuqing Huo,Chaodong Wu

Frontiers of Medicine 2015, Volume 9, Issue 2,   Pages 173-186 doi: 10.1007/s11684-015-0384-0

Abstract:

Metformin has been widely used as a first-line anti-diabetic medicine for the treatment of type 2 diabetes (T2D). As a drug that primarily targets the liver, metformin suppresses hepatic glucose production (HGP), serving as the main mechanism by which metformin improves hyperglycemia of T2D. Biochemically, metformin suppresses gluconeogenesis and stimulates glycolysis. Metformin also inhibits glycogenolysis, which is a pathway that critically contributes to elevated HGP. While generating beneficial effects on hyperglycemia, metformin also improves insulin resistance and corrects dyslipidemia in patients with T2D. These beneficial effects of metformin implicate a role for metformin in managing non-alcoholic fatty liver disease. As supported by the results from both human and animal studies, metformin improves hepatic steatosis and suppresses liver inflammation. Mechanistically, the beneficial effects of metformin on hepatic aspects are mediated through both adenosine monophosphate-activated protein kinase (AMPK)-dependent and AMPK-independent pathways. In addition, metformin is generally safe and may also benefit patients with other chronic liver diseases.

Keywords: metformin     diabetes     hepatic steatosis     inflammatory response     insulin resistance    

denitrification system with short-term pyridine exposure: Process capability, inhibition kinetics and metabolic

Frontiers of Environmental Science & Engineering 2021, Volume 15, Issue 6, doi: 10.1007/s11783-021-1433-3

Abstract:

• Short-term effect of the pyridine exposure on the SAD process was investigated.

Keywords: Anammox     Inhibition     Metabolic pathway     Microbial community     Pyridine     SAD    

Water-dispersible nano-pollutions reshape microbial metabolism in type-specific manners: A metabolic

Frontiers of Environmental Science & Engineering 2022, Volume 16, Issue 9, doi: 10.1007/s11783-022-1548-1

Abstract:

• Water-dispersible nano-pollutions exhibit type-specific toxic effects on E. coli.

Keywords: Nano-toxicity     Nano-plastics     Quantum dots     Microbial metabolite     Metabolic dysregulation    

The FGF metabolic axis

Xiaokun Li

Frontiers of Medicine 2019, Volume 13, Issue 5,   Pages 511-530 doi: 10.1007/s11684-019-0711-y

Abstract: Members of the fibroblast growth factor (FGF) family play pleiotropic roles in cellular and metabolicFGF19 metabolic axis from the ileum to liver negatively controls diurnal bile acid biosynthesis.FGF21 metabolic axes play multifaceted roles in controlling the homeostasis of lipid, glucose, and energyFGF23 axes from the bone to kidney and parathyroid regulate metabolic homeostasis of phosphate, calciumThus, the term “FGF Metabolic Axis,” which distinguishes the unique pathways and functions of endocrine

Keywords: FGF19     FGF21     FGF23     FGFR     metabolism     endocrine     Klotho    

Disturbance rejection via iterative learning controlwith a disturbance observer for active magnetic bearing None

Ze-zhi TANG, Yuan-jin YU, Zhen-hong LI, Zheng-tao DING

Frontiers of Information Technology & Electronic Engineering 2019, Volume 20, Issue 1,   Pages 131-140 doi: 10.1631/FITEE.1800558

Abstract: A disturbance observer based ILC scheme is proposed that consists of a universal extended state observer

Keywords: Active magnetic bearings (AMBs)     Iterative learning control (ILC)     Disturbance observer    

Regulation of T cell immunity by cellular metabolism

Zhilin Hu, Qiang Zou, Bing Su

Frontiers of Medicine 2018, Volume 12, Issue 4,   Pages 463-472 doi: 10.1007/s11684-018-0668-2

Abstract: Specific metabolic programs are tightly controlled to mediate T cell immune responses, and alterationsIn this review, we will summarize the main T cell metabolic pathways and the important factors participatingin T cell metabolic programming during T cell homeostasis, differentiation, and function.

Keywords: T cell immunity     metabolic pathways     nutrient uptake     metabolic checkpoints    

Title Author Date Type Operation

Polycystic ovary syndrome

Zi-Jiang CHEN, Yuhua SHI

Journal Article

Modal disturbance investigation of rod-shaped ultrasonic motor using bending vibrations

ZHANG Jiantao, ZHU Hua, ZHAO Chunsheng

Journal Article

New insights into different surfactants’ impacts on sludge fermentation: Focusing on the particular metabolic

Journal Article

Metabolic hypertension: concept and practice

Zhiming Zhu, Peijian Wang, Shuangtao Ma

Journal Article

Beneficial metabolic activities of inflammatory cytokine interleukin 15 in obesity and type 2 diabetes

Jianping Ye

Journal Article

electron transfer and its application in dictating routes of biochemical processes associated with metabolic

Journal Article

Virtual reality system of manned maneuvering unit taking into consideration the disturbance from an astronaut

CHENG Jian, FAN Xiu-min, XU An, HONG Xin, HUANG Wei-dong

Journal Article

Fibroblast growth factor 21: a novel metabolic regulator from pharmacology to physiology

Huating Li, Jing Zhang, Weiping Jia

Journal Article

Application of a Novel Fuzzy Clustering Method Based on Chaos Immune Evolutionary Algorithm for Edge Detection in Image Processing

Journal Article

Metformin and metabolic diseases: a focus on hepatic aspects

Juan Zheng,Shih-Lung Woo,Xiang Hu,Rachel Botchlett,Lulu Chen,Yuqing Huo,Chaodong Wu

Journal Article

denitrification system with short-term pyridine exposure: Process capability, inhibition kinetics and metabolic

Journal Article

Water-dispersible nano-pollutions reshape microbial metabolism in type-specific manners: A metabolic

Journal Article

The FGF metabolic axis

Xiaokun Li

Journal Article

Disturbance rejection via iterative learning controlwith a disturbance observer for active magnetic bearing

Ze-zhi TANG, Yuan-jin YU, Zhen-hong LI, Zheng-tao DING

Journal Article

Regulation of T cell immunity by cellular metabolism

Zhilin Hu, Qiang Zou, Bing Su

Journal Article